Perflow Medical Receives CE Mark Approval of Cascade Agile Net for Neurovascular Treatment


October 21, 2019—Perflow Medical, which is based in Israel, announced CE Mark approval for the Cascade Agile nonocclusive remodeling net.

According to the company, the Cascade Agile optimizes control for distal and tortuous vessel anatomy during coil embolization of intracranial aneurysms. The device is based on the company’s same technology platform used in Perflow Medical’s Stream Dynamic neurothrombectomy net and Cascade Net.

Perflow's Cerebral Net technology platform includes a braided net that enables adjustable neurovascular treatments, emphasizes physician expertise by combining real-time physician control, advanced device manipulation, full wall apposition, and excellent radiopacity to improve patient outcomes.

The company also announced that the publication of an article by Stanimir Sirakov, MD, et al in the Journal of NeuroInterventional Surgery reviewing clinical experience with the Cascade Net as a novel approach for the treatment of ruptured intercranial aneurysms.

Perflow Medical advised that its Cascade product family supports procedural efficiency with its unique net design that enables continuous blood flow during cerebral aneurysm repair and coiling. For distal aneurysms with tortuous anatomy, the Cascade Agile’s shorter braid length creates a more responsive device, which gives physicians the confidence and control they need to safely perform coil embolization.

The Cascade product family and Stream Net are commercially available across Europe for the treatment of intracranial aneurysms and acute ischemic stroke, respectively. Perflow products are not approved for clinical use within the United States.

Perflow is exhibiting the Cascade Net, Cascade Agile, and Stream Net at the World Federation of Interventional and Therapeutic Neuroradiology held October 21–24 in Naples, Italy.


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